In a large skillet over medium-low heat, combine the tomato sauce, garlic powder, dried oregano, and dried basil.
Bring the mixture to a simmer.
While the sauce is simmering, prepare the meatballs.
In a large bowl, combine the ground beef, shredded Parmesan cheese, beaten eggs, crumbled whole-grain bread, garlic powder, salt, and pepper.
Mix well and form the mixture into 2-inch meatballs.
Add the uncooked meatballs to the simmering sauce.
Allow them to simmer over medium-low heat for approximately 30 minutes, turning occasionally, until the meatballs are cooked through and no longer pink in the center.
In the meantime, cook the spaghetti according to the package instructions.
Notes / Tips / Wine Advice:
Once the meatballs are cooked, serve the flavorful sauce and meatballs over the cooked spaghetti.